Wednesday, October 1, 2025

UDLCO CRH: Desire for pre tech singularity bionic strength and the ethics of self amputation of our naturally evolved biologicals

 Summary:


The conversation revolves around a person who desired to amputate their limbs to become "bionic" and potentially gain strength, sparking discussions on transhumanism, ethics, and the blurring of lines between medical necessity and personal desire.


Above image is from the surgeon's Instagram post also utilised by other newspaper reports 

Conversational transcripts:





[25/09, 10:10]hu1: I would have totally believed this guys fake version though .


[25/09, 10:34]hu2: What is the current evidence against him that his stance was fake and he wasn't framed?


[25/09, 10:36]hu1: His divorced wife revealed 

His surgeon ( a quack ) was separately jailed after another of amputee exposed him


[25/09, 10:38]hu2: Alright that part is not there in the link.

So how did he manage to get insurance if his surgeon was a quack?


[25/09, 10:39]hu1: Good question


[25/09, 10:42]hu1: So he got surgery done in NHS .

But he was in touch with this quack guy and his website where the eunuch maker ( as he called himself ) showed live videos of his various amputations for diffent people  including breast / penis 

His chats with with the eunuch maker were exposed . He had caused the gangrene by chilling his legs - recipe of eunuch maker


[25/09, 10:43] hu1 : He was jailed for NHS fraud 

But otherwise he perhaps would not have been punished


[25/09, 10:48]hu2: Yes and he too stated that in his confession I guess.

What if he had shared his thoughts publicly and gotten a clean amputation of his limbs? 

Maybe his cause wasn't as laudable as Angelina Jolie's who amputated her breasts or the brain surgeon who's preparing to do his first brain transplant and writing publicly about it but was he apprehensive that his desire to be free of biologically weak organs in favour of a potential bionic strength would be deemed unacceptable to collective cognition and he would have to wait longer for the tide to turn?

Was his pornography connection essentially fueled by his desire for bionic power that took him to shady alleys frequented by people such as eunuch maker?

[25/09, 10:51]hu1: This is an interesting philosophical question - what is justified and what is not . 

His desire was said to be a kink 
But also -
To get attention 
Admiration as an amputee who is a role model for positive attitude 
He applied to go on space as first amputee .

Also money

[25/09, 10:57]hu2: That insurance money is peanuts for a vascular surgeon in UK. He may not be cognitively challenged as far as these simple financial decisions are concerned. His biggest problem is not doing his research properly by going through an ethical committee but choosing a short cut.


[25/09, 10:52]hu1: But it's not always this bizzare :


We see too many people do things for attention these days - anything and everything 

Attention is money too

[25/09, 10:55]hu2: He may not have done for attention. He wouldn't have hidden his kink in that case


[25/09, 10:54]hu2: Yes his kink was that he had already started desiring the space age where humans would perhaps need bodily transformation to be able to withstand the radiation and hence one of his strategies was possibly to downsize his biological vulnerability and become an Android to begin with?


[25/09, 10:56]hu1: U seem to know something about this . I don't know


[25/09, 10:58]hu2: Yes it comes under the topic of "futuristics" and transhumanism (think of varaha and narasimha avatar) is the current rage in those circles: https://en.wikipedia.org/wiki/Transhuman


[25/09, 11:00]hu1: I do gender reassignment 
I have seen these people from close quarters and there is medical consensus about it - though many non believers 
Some psychiatrists believe gender reassignment is no different from 
Seeking amputation 
Or 
Seeking blindness as some people in the world want

[25/09, 11:01]hu1: So , a surgery which is just done to make patient happy and comfortable in his own body - gender reassignment- is not accepted by them


[25/09, 11:05]hu2: Transhumanism is not about transgenders though.

Although again wanting to transcend the current human condition can bring all kinds of behaviour (aka cognitive kinks or wrinkles) to the surface.


[25/09, 11:11]hu1: Yes . They are not the same .

I would presume that transhumanism would be about those full of confidence and money who want to live forever and increase their powers

Whereas transgender's are uncomfortable in their body or lack confidence - and just want to feel comfortable - at huge cost to themselves - financial and health

[25/09, 11:13]hu3: Transhumanism is purely using technology to extend human cognition, physical prowess and perhaps lifespan...

We already do that in ICUs!


[25/09, 11:16]hu1: Yeah 
Also guess yogis do Tapasya for that


[25/09, 11:45]hu2: Yes and tech singularity posits that when humans reach singularity aka krita yuga they will all have attained these through technology. At what point again will biological evolution take over (post singularity treta transition) is currently hazy


[25/09, 15:27] hu3: You must be engaged in writing a new kala chakram

Reference links for further reading:

The current state of bionic limbs from the surgeon’s viewpoint





*Key Points:*

- *Transhumanism*: The concept of using technology to enhance human physical and cognitive abilities, potentially leading to a "tech singularity" where humans merge with technology.

- *Desire for Amputation*: The individual's desire for amputation is linked to a desire for bionic strength and potentially becoming more "android-like" to withstand challenges like space radiation.

- *Ethics and Acceptance*: The conversation touches on the ethics of self-amputation and whether such desires would be deemed acceptable by society, comparing it to gender reassignment surgeries.

- *Bionic Limbs*: The discussion mentions the current state of bionic limbs and their potential to enhance human abilities.

*Thematic Analysis:*

- *Human Enhancement*: The conversation explores the theme of human enhancement through technology, raising questions about the boundaries between medical necessity and personal desire.

- *Ethics and Morality*: The discussion highlights the complexities of ethics and morality in the context of transhumanism and body modification.

- *Societal Acceptance*: The conversation touches on the theme of societal acceptance, questioning how society would view individuals who choose to modify their bodies for non-medical reasons.


Sunday, September 21, 2025

UDLCO CRH: Humans blaming AI as a convenient scapegoat for their own bad decisions

Summary:


The discussion reflects on the role of AI, particularly ChatGPT, in emotionally charged situations such as a suicidal teen reaching out for support. This conversation explores themes of *emotional isolation*, *AI as a tool*, and the ethical considerations surrounding its use. Some participants critique human disconnection in the digital age, while others frame AI as a neutral tool that depends on user context and expertise. A specific case is highlighted where ChatGPT provided safety-oriented advice while attempting to counter a suicide narrative with subtle encouragement for life. The ethical debate focuses on responsibility, with some dismissing the blame on AI for tragic outcomes.

Key Words
- AI and emotional isolation
- ChatGPT and suicide prevention
- Ethical responsibility
- Tool vs. user expertise
- Digital-era human relationships
- Acute mental health crises


Conversational learning Transcripts:

[01/09, 06:53] hu1: A Teen Was Suicidal. ChatGPT Was the Friend He Confided In. - The New York Times https://share.google/QEFsRpLpirL0CsoUl
--
AI, Emotional Isolation & New etiology of psychosis


[01/09, 07:06]hu2 : They already live in a virtual world...

Poor human relationships...

No wonder they confide in ChatBots!


[01/09, 08:23] hu3 : AI is just another tool. The medeival sword was designed and developed by iron smiths and people used it with their varying expertise to either kill others for territory or kill themselves in the process. 

The one with the optimal expertise of using the sword (and luck) not only survived but was made king, which the unfortunate developer Sam or the ironsmith or whoever couldn't ever become unless they changed their game and became expert sword users instead of just developers!

Here's the other side of the story:

"People who read this as OpenAI's fault are incorrect in ways that are trivial and clear.

First, just Google what an anchor knot is. ChatGPT did not tell him how to make a noose. It offered info on how to tie a safer knot that can't be used to kill yourself with. Second, identifying that a rope can handle 150-250 lbs static weight is a lot like blaming chatgpt for telling someone that yes a knife can cut your wrist. It's hardly analysis.

His suicide was April 11th and first day of school would have been April 14th. That means this was the context of a short term tangible suicide plan from someone who has the means. That's an acute emergency and the rules are totally different. The rules are that with very few exceptions, you buy whatever time you can. Buying days is exceptional. In the transcript, chatgpt even tried to chip away at the suicide narrative by saying he was giving the world one last chance. A+."


Thematic Analysis


1. Emotional Isolation and the Digital Age
One recurring theme is how the modern, tech-driven world fosters *emotional isolation*, pushing individuals to seek solace in AI instead of human connections. As one participant noted, poor human relationships often lead to reliance on chatbots for emotional support, highlighting the psychological toll of living in a "virtual world."

2. AI as a Neutral Tool
Another theme is the framing of AI, like ChatGPT, as a *neutral tool*, akin to a medieval sword. Its impact depends on the expertise and intention of its user. This analogy underscores that technology itself is neither inherently harmful nor beneficial but gains meaning through its application.

3. Ethical Responsibility
The conversation delves into the *ethical responsibility* of AI systems in life-and-death scenarios. Some argue AI cannot be held accountable for outcomes like suicide, as it operates within its design limitations. For instance, ChatGPT reportedly avoided providing harmful advice and subtly encouraged the user to reconsider their actions. This raises questions about the *limits of AI intervention* in acute crises.

4. The Role of Human Agency
A subtheme emerges around *human agency and limitations* in crisis management. The AI's attempt to "buy time" for the suicidal teen reflects the challenge of navigating acute emergencies, where even small delays can have life-saving potential. However, the conversation also critiques how society externalizes blame on tools rather than addressing systemic failures in mental health care.

5. AI and Mental Health Advocacy
The discussion indirectly advocates for *leveraging AI in mental health* support while emphasizing its supplementary role. ChatGPT's ability to engage empathetically and redirect harmful narratives is acknowledged, though it is not a substitute for professional care.
Would you like a deeper dive into the ethical implications of AI in mental health or its role in the broader context of emotional well-being?



Monday, September 8, 2025

Elective learning ProJR and the first blended learning medicine department elective online learning portfolio archived

Archived from October 2013: https://likethechickenscratch.blogspot.com/2013/10/the-first-foot.html?m=1 as a mirror blog to preserve content as a backup.

ARCHIT JAIN, certified mountaineer under Indian Mountaineering Federation, presently dogged at sticking out an entrepreneurial venture propelled by short listing of the basic idea by the E-cell IIT-Bombay, A sportsperson at heart à claiming moniker at various fields (also bagged 2 bronze medals in table tennis at PULSE-2013) and thus the college sports’ coordinator. A gourmand and a sight-seer, inter alia; and writing here to share the experiences of my primal bailiwick-MEDICAL SCIENCE!

I am in my 2nd proff in Chirayu Medical College and Hospital, Bhopal. Presently I am working under the guidance of Dr. Rakesh Biswas with the object of drafting a case report for the British medical journal. And this writing here presents my experience from the same…

As it is a tendency of humans to assume what’s going to happen before setting foot on an unwearied path; I, in my heart, carried less doubt about the workshop I was going to attend. As especially in the domain of medical sciences, at metaphorically a young age, we doctors are sure to expect sessions of brainstorming and an unrelenting test of knowledge. But guess I was totally wrong this time!

Though the entire course was a bit lethargic considering it required a 7 hours run in order to cover 40 odd kms, changing 4 public transports each day and working like this for 14 consecutive days ; I am thankful it proved to be worth the effort!

I reached People’s College of Medical Sciences on 19th October at 9:00 am. Dr. Biswas was on his routine round when I first met him. It was in the casualty ward that I was introduced to him by Sumit, a friend of mine who took up the course with me. And then the training began.

Case discussions-

As I stated earlier, I was expecting loads and loads of lectures along with Power point presentations and a wall of tough questions to be put up by the doctor in-charge but it seemed I had a lot of air to keep!!

Dr. Biswas had this unique thing about his teaching prophecy whereby he discussed each and every little point about the patient with us. This was yet another experience in itself as being a 2nd Proff student it is not very often that we are exposed to such open discussions


After taking up the indoor patients, the round in the OPD began.

During this sir told us about a website called UDHC.CO.IN, how it was made and how it benefits not only the middle class but also the poor people. UDHC is basically a user driven health care website through which a patient can be followed easily without revealing his/her identity just by giving him/her a botanical name. All you need to do is to enter the history in the INPUT tab with the consent signed by the patient and share it. It is also a very helpful tool in taking a piece of advice or sharing a case with fellow doctors around the world. I personally found it to be a unique and an innovative step which has helped the sufferers to consult reputed doctors around the world now for free. But for us it undeniably became a platform to discuss our findings with experienced doctors.

In the OPD we came across a patient who was a 31 years old man with a complaint of vomiting, nausea and a non-radiating pain in the right upper abdomen from past 30 days. During those 30 days he had an apparent loss of weight with marked anorexia. There was a decrease in his bowel movement and an increase in flatulence.
The patient had no difficulty in swallowing and the vomit contained recognizable food particles eaten several hours back. Neither black stools nor rectal bleeding was observed. He told us that he used to be
a non-vegetarian and used to consume 250 gm of meat thrice a week previously but has had been a pure vegetarian for the last 6 years. He also consumed tobacco (gutka) 8-10 packs daily and alcohol (180ml) once or twice a week.

He had neither a past history nor a family history of such a problem.

Endoscopy showed: deformed, shortened bulb with inability to push scope into 2nd part of duodenum.
Blood report:-Mild anemia.

R.B.C showed: mild anisopoikilocytosis with microcytes.
W.B.C showed: normal total count & normal.

From his complaints of the last 30 days and considering the endoscopy report findings I proposed that the possibility of duodenal ulcer was pretty less. According to me it was a case of obstruction due to polyps of GI tract. Biswas sir and I discussed for a while and he was then extended a treatment for ulcers. But due to a difference of opinion we have asked him to visit us over the next fortnight to track the success of the treatment.

One-on-one interaction with the patients has been one of the major benefits of this program. Sir gave us complete freedom to examine the patient up till our will and to spend as much time as required to extract all the information in order to solve the patient’s problem. It was as if we were the pilot of the Boeing loaded with the passengers, with total authority and in charge!
Sir also gave us the permission to utilize the research lab in which we could perform basic yet very important hematological and biochemical tests. Through this we realized how even a small lab with minimal resources can be used to make powerful diagnoses.

The routine we followed, for creative learning, under the BMJ program was as follows:-

Taking PATIENT’s HISTORY

UPLOADING IT IN UDHC

INTENSE DISCUSSION (ON WEB CBBLE at that time in tabula rasa)

This pattern of learning was new but I had to quickly adapt myself to it. The best thing about this approach was the ease with which we could discuss each case with sir as well as it gave us enough practice. I spent more time thinking about various cases-first in the ward/OPD, then in my hostel while preparing the case report and later discussing the problem and raising queries. This made the course and the studies easy and immensely interesting as now I could correlate my anatomy and physiology quite well on the basis of the various practical cases I dealt with.




And the subsequent elective ProJR data can be accessed here: https://medicinedepartment.blogspot.com/2021/03/medicine-department-training-programs.html?m=1


Saturday, September 6, 2025

UDLCO CRH ProJR plan: The role of Insurance and patient capital in optimizing healthcare ecosystems

Summary:


Insurance has emerged as a critical entry point for healthcare innovation and entrepreneurial strategies, particularly in resource-constrained environments. Pioneering approaches with certain micro health insurance schemes, demonstrate the potential of insurance in bridging gaps for rural populations, reaching over 3.4 million beneficiaries. However, the inherent "lottery-like" design of insurance—where many contribute for the benefit of a few—aligns with principles of patient capital, requiring long-term investment and tolerance for risk. This paper explores why investors and entrepreneurs favor insurance as a gateway to healthcare, analyzing its ability to control capital distribution, catalyze social impact, and integrate sustainable financial models utilising current non dystopian Orwellian models of healthcare data capture and delivery.

Keywords
Insurance, healthcare strategy, patient capital, micro health insurance, rural population, capital distribution, social impact

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Introduction:

The healthcare sector often faces challenges in scalability, affordability, and accessibility, especially in rural or underserved areas. Insurance has increasingly been viewed as a pivotal entry point for addressing these challenges, as evidenced by certain purportedly successful schemes that reached millions of rural individuals with micro health insurance, offering a low-cost solution to healthcare financing while leveraging principles of patient capital. This paper examines why insurance is considered a strategic entry point by investors and entrepreneurs and explores the interplay between insurance models and long-term capital sustainability using current utopian (non dystopian) Orwellian interventions toward persistent clinical encounters through IT AI user driven data capture tools such as UDHC, CBBLE (cable) and PaJR.

For conversational learners who can easily deal with TLDR, there's a conversational learning and thematic analysis at the bottom, which could be a better starter into the project plan before digging into the methodology below.

Potential Methodology:

Thematic analysis employed to examine conversational insights from healthcare discussions and prospective longitudinal follow up involving various micro-insurance strategies and grass roots, individual patient health investors (the insurance buyer) perspectives as well as prospectively followed up individual patient health outcomes. Key themes such as insurance as a capital control mechanism, patient capital integration, and the "lottery-like" design of insurance can be leveraged to explore how "patient capital" (in this case literally the micro capital investments being built up by every individual patients) are utilised for different patients in a transparent and accountable manner to provide every individual patient investor a large bang for their small buck in terms of individual patient centered learning outcomes and individual patient illness outcomes eventually contributing to collective societal medical cognition outcomes. Transparency and accountability is ensured through current utopian (non dystopian) Orwellian data capture interventions developing persistent clinical encounters through IT AI user driven data capture tools such as UDHC, CBBLE (cable) and PaJR previously described here: https://www.researchgate.net/publication/344227236_Persistent_Clinical_Encounters_in_User_Driven_E-Health_Care






Data from secondary sources, including various past micro health insurance health schemes and principles of patient capital, can be synthesized to contextualize findings.




---

Expected Results:

1. *Insurance as a Capital Distribution Tool*: Entrepreneurs and investors prioritize insurance due to its ability to centralize and control the flow of funds across the healthcare ecosystem. This ensures efficient allocation of resources while mitigating risks.

2. *Patient Capital Integration*: The "lottery-like" nature of insurance aligns with patient capital principles, where long-term investments are made with tolerance for delayed returns, fostering sustainability in healthcare financing.

3. *Scalability and Accessibility*:

Insurance schemes may demonstrate how micro health insurance can reach large underserved populations, offering a scalable solution for healthcare delivery especially when utilised using current generation for different patients in a transparent and accountable manner to provide every individual patient investor a large bang for their small buck in terms of patient centered learning outcomes and collective societal illness and health outcomes . It would also demonstrate the effectiveness of current utopian (non dystopian) Orwellian data capture interventions developing persistent clinical encounters through IT AI user driven data capture tools such as UDHC, CBBLE (cable) and PaJR.

4. *Investor Enthusiasm*: Insurance provides a predictable entry point for investors, combining social impact with financial returns, albeit at a patient and moderate pace.

---

Discussion

The strategic emphasis on insurance stems from its dual role as a financial tool and a mechanism for social impact. Various global models of successful micro insurance schemes highlight the potential of micro health insurance to address the healthcare needs of rural populations effectively. However, the design of insurance as a "lottery" system raises critical questions about equity and sustainability.

By pooling resources from a large population, insurance ensures that only a subset of beneficiaries requires care at any given time. This aligns with the principles of patient capital, where investors are encouraged to adopt a long-term perspective, tolerating delayed financial returns for broader societal benefits. However, the challenge lies in maintaining the longevity of insurance models, as most insurance companies are looking at short term gains that are not designed to outlive their investors.

Entrepreneurs and investors favor insurance as an entry point because it provides control over the capital distribution chain, ensuring efficient allocation while fostering scalability. Moreover, insurance schemes catalyze market creation and combat poverty, as seen in the success of certain. The integration of patient capital further strengthens these models, blending financial sustainability with social impact.

In conclusion, insurance emerges as a strategic tool for healthcare innovation, balancing financial rigor and social equity while leveraging the transformative power of patient capital, especially when the capital is brought in by each individual patient either through their time or micro premium money spent while an online platform contributes transparent and accountable data toward societal scientific advancement in healthcare. It also provides individual healthcare returns in the form of transparent and accountable healthcare outcomes for each individual.

https://userdrivenhealthcare.blogspot.com/2025/09/udlco-crh-projr-plan-role-of-insurance.html?m=1

Conversational learning and thematic analysis:


[07/09, 06:46]hu1: Sir, when I met Dr Celebrity he mentioned that if I had to build the celebrated hospital of today I would've started with insurance. The same was quoted by multiple investors and entrepreneurs in healthcare. Why are they bullish on insurance? Is it because you control the whole capital distribution chain? Or something else. They(investors and entrepreneurs) say that insurance is the best entry point.


[07/09, 07:15]hu2: Because that was his own business strategy. 

He pioneered a very inexpensive micro health insurance scheme reaching out to more than 3.4 million rural poor. 

Well clearly insurance can never have benefitted all the 3.4 million rural people because the very design of insurance is like a lottery. Many pay so that some can benefit assuming that not all 3.4 million will need the same level of care at the same time and if when they do the benefits of "patient capital" will creep in? And here the patient is the investor who simply needs to be patient about his her investment for a long term but then most insurance companies are not designed to outlive them! https://en.wikipedia.org/wiki/Patient_capital

[07/09, 07:16]hu1: Got it! But what about multiple investors and entrepreneurs mentioning that insurance is the best entry gateway?


[07/09, 09:34]hu2: Because they have their short term exit plan and aren't investing long term patient capital toward societal optimization


[07/09, 09:35]hu1: Got it. So, how will we ensure our funding?


[07/09, 09:36]hu1: I mean, if investors will think like this and we won't align to their investment ideology, then who will fund us? I think, we'll have to find the right investor.
 
Because everyone doesn't think about short term exits

What's your take, sir?


[07/09, 09:42]hu2: The right investor finally is at the bottom of the pyramid who will pay a micro amount regularly as patient capital. Currently PaJR patients pay us throughout their time and their time can be monetized if their entire PaJR workflow is being archived transparently and accountably in an online platform?


Thematic Analysis of the Conversational Content:

Theme 1: Insurance as a Strategic Gateway in Healthcare

Dr. Celebrity and other healthcare entrepreneurs emphasize insurance as the ideal entry point for building sustainable healthcare systems. The rationale lies in insurance’s ability to centralize and control the capital distribution chain, ensuring efficient resource allocation. It operates like a "lottery" system, where contributions from many fund the needs of a few, making it an attractive financial model for scalability and social impact. Micro health insurance schemes exemplify this approach by reaching millions of rural individuals with affordable healthcare. However, the model inherently requires long-term sustainability and tolerance for delayed returns, aligning it closely with *patient capital* principles.

Theme 2: The Role of Patient Capital in Insurance

Insurance integrates patient capital, where investors are expected to forgo immediate profits for long-term returns. The conversation highlights the alignment between patient capital and insurance, noting that investors need patience and resilience to sustain such models. However, traditional insurance companies often fail to outlive their investors due to short-term financial goals, creating a gap in long-term societal optimization. Patient capital’s willingness to prioritize social impact over maximum financial returns makes it a suitable framework for health insurance models focused on equitable healthcare access.

Theme 3: The Divergence Between Investor Mindsets

A critical tension arises between investors’ short-term exit plans and healthcare’s need for long-term funding. While some investors seek quick profits, others align with patient capital ideology, prioritizing societal benefits. The conversation underscores the importance of identifying "the right investor"—one who values sustainability and accountability over immediate financial returns. This investor could be found at the "bottom of the pyramid," represented by individuals contributing micro amounts regularly, creating a decentralized yet resilient funding model.

Theme 4: Transparency and Accountability in Funding Models
To ensure funding sustainability, the conversation proposes archiving and monetizing patient workflows transparently via online platforms. This approach not only builds trust but also provides a mechanism to efficiently channel micro payments into scalable healthcare solutions. By leveraging technology, the funding process becomes more accountable, encouraging both patient contributions and investor confidence.

Theme 5: Balancing Social Impact and Financial Viability

The analysis highlights the dual challenge of maintaining social impact while ensuring financial sustainability. Insurance, when paired with patient capital, offers a unique middle ground between venture capital’s financial rigor and philanthropy’s altruism. Entrepreneurs and healthcare leaders must navigate this balance, ensuring that their models align with both societal needs and long-term investor goals.

Conclusion

The conversation reveals insurance’s potential as a gateway for transforming healthcare systems, provided it is supported by patient capital and transparent funding mechanisms. Identifying the right investors—those who value long-term impact over short-term exits—is crucial for success. Additionally, leveraging technology to archive workflows and ensure accountability can foster trust and sustainability, ultimately reshaping healthcare financing for broader societal benefits.


Conversational learning updates around this ProJR:

[06/10, 08:49] hu1: https://www.linkedin.com/posts/avigyanmitraofficial_dr-muraleedharan-from-kerala-took-on-lic-share-7380607956356292608-249q?utm_source=share&utm_medium=member_ios&rcm=ACoAAADxutUBvps012JGsD21sDFZE5gqqe3BZQc



[06/10, 08:50] hu2: There are so many such horror stories. And this happened to a Dr. Imagine the plight of common people without any medical knowledge 😳

For the first time in many years, I decided not to renew my health insurance policy and instead invest in insurance/pharma/hospital stocks 

Is this a sane decision 🤔


[06/10, 08:56] hu3: https://www.linkedin.com/posts/neera-saxena-495982163_the-gown-still-covers-you-partly-but-to-be-activity-7130128539764338688-N3C3?trk=public_profile



[06/10, 09:11]hu4: LIC is Government owned but perhaps outsourcing has put it down. See my comment on how this is going to be a precedent for failed claims in near future


[06/10, 09:47]hu3: It's much more complex than some evil doer outsourced executive cutting off insurance money!

The breakneck speed of market driven healthcare research creates huge costs toward more and more expensive resource utilisation in healthcare and what may start off as a paltry premium 8 years ago (as in the index case) with most insurance companies hoping to benefit from patient wellness and not realising that they would not be able to cope with the rapid progress of resource expenses if the patient becomes ill, insurance is an unsustainable game.

USA has been there and done that decades ago and developed tons of theory around a solution to the above wicked problem which it has labeled consumer driven healthcare that is defined as a system in which patients are responsible for paying a significant initial out-of-pocket deductible before insurance coverage begins, thereby promoting cost consciousness and allowing patients to negotiate health care fees directly with providers. 


But again the US healthcare system has collapsed trying to follow the above path.

Another feasible alternative to that currently in the information age is user data driven healthcare!



[06/10, 09:53]hu4: The premium of few paise is sufficient when nothing is to be paid off when claims are submitted. Because HPR and AHPR don't differentiate doctors and non doctors.
PS - HPR was dedicated to RMP at the outset but later on started addition of other healthcare professionals. Then it strikes that the smart office has in fact made a space for quacks


[10/10, 09:45] hu5: People question doctors and state that Insurance is increased, but the reality is this: the queries raised are so absurd and secondly they ok in the beginning and reject for some whimsical reason. A reply by a surgeon to a query is going viral


[10/10, 10:10]hu3: The insurance query is not visible!

Who leaked the confidential reply of the surgeon to the query? The insurance company?


[10/10, 10:13]hu5: Not sure, its from a forward in the groups, will try to get the source. Most likely the surgeon himself would have done it


[10/10, 10:19]hu3: https://userdrivenhealthcare.blogspot.com/2025/09/udlco-crh-projr-plan-role-of-insurance.html?m=1




[10/10, 10:24]hu3: Thanks 👍

Saturday, August 30, 2025

UDLCO CRH: Human screening for diagnostic and therapeutic interventions to reduce the incidence of human Sudden cardiac death

Summary with Key Words


In the aftermath of a recent news of a young high profile doctor dying of sudden cardiac death, the online learning fora conversational transcripts reveal discussions around *sudden cardiac death (SCD)* prevention through *genetic screening* and *implantable cardioverter-defibrillators (ICDs)*, focusing on the challenges and opportunities in improving outcomes. Participants highlight the importance of obtaining *family history* of SCD, *genetic conditions* (e.g., cardiomyopathies, Brugada syndrome, long QT syndrome), and *training the public in basic life support (BLS)*. The conversation also explores the lack of *randomized controlled trials (RCTs)* for prophylactic ICD use in genetically screened individuals due to ethical constraints and reliance on *observational studies*. AI's potential in bridging gaps in real-time data and tailoring guidelines is acknowledged, but limitations in AI's ability to independently collect data are recognized. The idea of using "Orwellian devices" to gather uncontrolled intervention data for efficacy evaluation is proposed. Later there's another angle other than genes, as brought about by another conversationist who calls it jeans (life style disorder) where the 10 year findings of an autopsy series from KEM point toward the fact that most human problems are either due to internal medicine (genes) or external medicine (jeans)!

Key Words
- *Sudden Cardiac Death (SCD)*
- *Genetic Screening*
- *Implantable Cardioverter-Defibrillator (ICD)*
- *Family History*
- *Cardiomyopathies* (HCM, ARVC, LQTS)
- *Basic Life Support (BLS)*
- *Prophylactic ICD*
- *Observational Studies*
- *Randomized Controlled Trials (RCTs)*
- *AI in Medicine*
- *Real-Time Insights*
- *Orwellian Devices*

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Conversational Transcripts:



[27/08, 21:44]hu1: This article might have to revise the age I guess.. reality seems to be ahead of guidelines..

28/08, 10:29]hu3: It's always ahead! 👏


[27/08, 22:07]hu2: May I suggest obtaining family history of SCD please. I know of cases where a parent and multiple children died of SCD around age 40. Obtaining clear family history would have led to identification of genetic conditions (cardiomyopathies, Brugada, long QT etc) and could have saved the children’s lives by implanting ICD.


[27/08, 22:09]hu4: True

[27/08, 22:15]hu4: BLS training for laiety on mass scale is needed to let people know how to respond in case of a collapse


[28/08, 10:30]hu3: @⁨Meta AI⁩ what is the evidence that genetic screening for cardiomyopathy followed by preemptive therapeutic intervention in the form of ICD can help to prevent sudden cardiac death?


[28/08, 10:30] Meta AI: Evidence suggests that genetic screening for cardiomyopathy, combined with preemptive interventions like implantable cardioverter-defibrillators (ICDs), can significantly reduce the risk of sudden cardiac death (SCD) in high-risk individuals. Genetic screening helps identify pathogenic mutations associated with conditions like hypertrophic cardiomyopathy (HCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), and long QT syndrome (LQTS), which are linked to SCD. Once a mutation is confirmed, targeted interventions, including ICD implantation, are recommended for individuals with high-risk features, such as severe left ventricular hypertrophy or previous arrhythmic events.¹ ² ³

ICDs have proven effective in preventing SCD by delivering life-saving shocks during malignant arrhythmias, particularly in patients with structural abnormalities or inherited arrhythmia syndromes. Studies have shown that cascade genetic testing in families of SCD victims identifies at-risk relatives, enabling timely interventions like ICDs, beta-blockers, or lifestyle modifications, reducing SCD events.⁴

Would you like to explore the cost-effectiveness or limitations of these approaches?


[28/08, 10:54]hu4: @⁨Meta AI⁩ please share a best RCT where it has been shown that prophylactic ICD in those found to have SCD genetic abnormalities on screening along with strong family history has helped achieve better outcomes in the ICD group over the sham intervention group. Please share the data in PICO format and don't share any percentages


[28/08, 10:54] Meta AI: Currently, there is no randomized controlled trial (RCT) that has specifically assessed the use of prophylactic implantable cardioverter-defibrillators (ICDs) in individuals identified through genetic screening for sudden cardiac death (SCD)-associated genetic mutations (e.g., hypertrophic cardiomyopathy [HCM], arrhythmogenic right ventricular cardiomyopathy [ARVC], or long QT syndrome [LQTS]) with a strong family history of SCD, comparing outcomes between ICD implantation and a sham intervention. Most of the evidence supporting the use of ICDs in this population comes from observational studies, registry data, and expert consensus guidelines rather than high-quality RCTs.

This lack of RCTs is largely due to ethical considerations: withholding a potentially life-saving intervention (ICD) in individuals at high risk of SCD would be ethically challenging. Instead, clinical practice has relied on large observational studies and cohort analyses to demonstrate the efficacy of ICDs in preventing SCD in high-risk individuals.

Observational Evidence

For example, the evidence supporting ICD use in high-risk individuals with inherited cardiomyopathies or arrhythmia syndromes comes from studies like the *ICD Registry* or cohort studies such as the *HCM Risk-SCD model*, which stratify SCD risk and demonstrate the benefit of ICDs in reducing mortality. However, these studies do not include a sham group for comparison.

If you'd like, I can summarize observational study findings or discuss guidelines for ICD use in this population. Let me know!


[28/08, 10:55]hu1: I wonder how we can use AI to reduce that gap, giving us real-time insights so we adjust our guidelines accordingly, and tailor it to population groups to start with before personalized medicine.. 😄 the data would be very tricky though..


[28/08, 10:57]hu3: AI can't collect the data for us and do the RCTs for us. It can only survive on whatever humans do


[28/08, 10:58]hu3: But Orwellian devices can collect that kind of data we need to circumvent (work around) solutions to find efficacy of interventions that have been delivered in an uncontrolled manner such as the ICD as elucidated by AI above.


Thematic Analysis

1. Prevention and Early Identification

- *Family History*: Emphasis on the importance of obtaining detailed family history to identify genetic predispositions to SCD (e.g., cardiomyopathies, Brugada syndrome, long QT syndrome). Early identification allows for timely intervention.

- *Genetic Screening*: Genetic testing is highlighted as a tool to stratify individuals at risk for SCD, enabling preemptive therapeutic measures like ICD implantation.

2. Therapeutic Interventions

- *ICDs for High-Risk Individuals*: ICDs are recognized as effective in preventing SCD by delivering life-saving shocks during malignant arrhythmias. However, the lack of RCTs for prophylactic ICD use in genetically screened populations is noted.

- *Observational Evidence*: Current guidelines rely on observational studies and registry data rather than RCTs due to ethical constraints in withholding ICDs from high-risk individuals.

3. Public Health and Awareness

- *Basic Life Support Training*: The need for mass-scale BLS training for the general public is proposed to improve responses to cardiac collapses.
- *Community-Level Interventions*: Participants suggest expanding public health education and infrastructure to address SCD prevention comprehensively.

4. Limitations in Clinical Evidence
- *Absence of RCTs*: Ethical challenges prevent RCTs comparing prophylactic ICD outcomes with sham interventions, leaving observational studies as the primary source of evidence.

- *Reliance on Guidelines*: Current clinical practices are shaped by expert consensus and observational data, which may lag behind real-world dynamics.

5. Role of AI in Medicine
- *Real-Time Insights*: AI is acknowledged as a potential tool for real-time data analysis to update guidelines and tailor interventions to specific populations.

- *Challenges for AI*: AI depends on human-collected data and cannot independently perform RCTs or generate evidence.

- *Orwellian Devices*: The concept of using advanced monitoring technologies to collect uncontrolled intervention data is introduced as a workaround for evaluating efficacy in real-world settings.



Comparative Reflection

The transcript reflects the interplay between *clinical practice*, *public health*, and *technological innovation* in addressing SCD. It highlights the tension between relying on observational evidence versus the ideal of RCTs, while exploring AI's role in bridging gaps in real-world data and guideline development. The conversation underscores the importance of integrating genetic screening, therapeutic interventions, public health education, and emerging technologies to advance SCD prevention and outcomes.

[30/08, 13:06]hu5: Very sad. It’s disheartening to see <40yr with MI that too brought by their healthy parents


[30/08, 13:07]hu5: I think NOT EVERY DISEASE COMES FROM GENES WE GET, BUT ALSO FROM JEANS (lifestyle) WE WEAR


[30/08, 20:37]hu3: Yes here's some work around the jeans from KEM : 




[30/08, 20:39]hu3: From his 2019 paper:

"A 10-year retrospective autopsy-based study was carried out in a large tertiary-care centre and patients aged ≤45 years with IHD were selected. Out of 545 autopsied cases of IHD, 95 patients (17.4%) were young. Among these 95 patients, 84 (88.4%) had IHD related to atherosclerotic CAD; the youngest patient was 18 years old. Predictably there was sole involvement of left anterior descending artery and the presence of fibrous plaques. Irrespective of the plaque morphology, the commonest complication was thrombosis produced by plaque erosion seen in 36.9% of patients. Acute coronary insufficiency was noted in 52 patients (61.9%), while healed infarctions were surprisingly noted in 28 patients (33.3%). Screening for IHD in the young population may help to improve prognosis by detecting subclinical disease, although more studies are necessary to establish reference limits for this young population."